Latest Oncology News

Ongoing Research Could Help Define the Role of Immunotherapy in Earlier-Stage HCC

Ongoing Research Could Help Define the Role of Immunotherapy in Earlier-Stage HCC

November 21st 2024

Ashley Chan

James J. Harding, MD, discusses how immunotherapy could play a role in earlier stages in hepatocellular carcinoma.

Afami-Cel Shows Durable Persistence and Tumor-Killing Abilities in Synovial Sarcoma

Afami-Cel Shows Durable Persistence and Tumor-Killing Abilities in Synovial Sarcoma

November 21st 2024

Ashling Wahner

Treatment with afami-cel was associated with long-term persistence in the periphery that led to clinical benefit in patients with synovial sarcoma.

Trastuzumab Deruxtecan Advances HER2+ Gynecologic Cancer Care: With Susana M. Campos, MD, MPH

Trastuzumab Deruxtecan Advances HER2+ Gynecologic Cancer Care: With Susana M. Campos, MD, MPH

November 21st 2024

Susana Campos, MD, MPH

Dr Campos discusses clinical implications from the gynecologic cancer cohorts of DESTINY-PanTumor02 and considerations for managing adverse effects in patients receiving T-DXd.

Olaparib Leads PARP Inhibitor Charge in the Treatment of BRCA-Mutated, HRD Ovarian Cancer

Olaparib Leads PARP Inhibitor Charge in the Treatment of BRCA-Mutated, HRD Ovarian Cancer

November 21st 2024

Ashling Wahner

Whitney Goldsberry, MD, discusses patient characteristics and disease factors that sway the decision between available PARP inhibitors in ovarian cancer.

Dana-Farber Cancer Institute Faculty Among World's Most Highly Cited Researchers for 2024

Dana-Farber Cancer Institute Faculty Among World's Most Highly Cited Researchers for 2024

November 21st 2024

Dana-Farber Cancer Institute

Dana-Farber Cancer Institute announced that 42 of its researchers have been named to the Highly Cited Researchers list of 2024.

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EMA Grants PRIME Designation to NX-5948 for R/R CLL/SLL

November 21st 2024

Ryan Scott

NX-5948 has received PRIME designation from the EMA for the treatment of relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

FDA Accepts sNDA for Darolutamide Plus ADT in Metastatic Hormone-Sensitive Prostate Cancer

November 21st 2024

Chris Ryan

The FDA has accepted a sNDA for darolutamide plus ADT in metastatic hormone-sensitive prostate cancer.

An Era of Firsts in CML: Asciminib Challenges SOC TKIs

November 21st 2024

Megan Hollasch

Jorge E. Cortes, MD, details how asciminib is improving upon first- and second-generation SOC TKIs in chronic myeloid leukemia.

PYX-201 Generates Responses in Pretreated Advanced HNSCC and Other Solid Tumors

November 21st 2024

Chris Ryan

PYX-201 produced responses in heavily pretreated head and neck squamous cell carcinoma and other solid tumors.

Kidney Cancer NCCN Guidelines Receive Major Updates, Prostate Cancer Adds Targeted Agents

November 21st 2024

Megan Hollasch

Sandy Srinivas, MD, details updates from 2024 in the kidney and prostate cancer NCCN guidelines and agents/trials to look forward to in 2025.

FDA Approves Zanidatamab for Previously Treated, Unresectable or Metastatic HER2+ Biliary Tract Cancer

November 21st 2024

Chris Ryan

The FDA has granted accelerated approval to zanidatamab for pretreated, advanced HER2-positive biliary tract cancer.

Osimertinib Approaches EU Approval in Locally Advanced EGFR+ NSCLC After Chemoradiation

November 20th 2024

Caroline Seymour

Osimertinib has been recommended for approval in patients with locally advanced, unresectable, EGFR-mutant NSCLC after chemoradiation.

Lisaftoclax NDA Accepted for Review in China for Relapsed/Refractory CLL/SLL

November 20th 2024

Kristi Rosa

An NDA for lisaftoclax in relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma has been accepted for review.

Expanded Indications for CAR T-Cell Therapies Shepard in New Era of Myeloma Care

November 20th 2024

Ryan Scott

David R. Oveisi, MD, discusses how the expanded indications for ide-cel and cilta-cel are affecting treatment decision-making in multiple myeloma.

STK-478 May Be an Effective, Tolerable Treatment Alternative in PIK3CA-Mutant Breast and Gynecologic Cancers

November 20th 2024

Courtney Flaherty

Alberto Montero, MD, MBA, CPHQ, discusses the potential role for STX-478 in PIK3CA-mutant breast and gynecologic cancers.

How the Drive to Connect the Oncology Community Built an Educational Podcast Platform: With D. Ross Camidge, MD, PhD; and Rahul Gosain, MD, MBA

November 20th 2024

D. Ross Camidge, MD, PhD

Drs Camidge and Gosain discuss how Dr Gosain harnessed social media to create a podcast with practice updates for up-and-coming oncology professionals.

Zorifertinib Receives NMPA Approval for EGFR+ NSCLC With CNS Metastases

November 20th 2024

Courtney Flaherty

Zorifertinib has received NMPA approval in the first line for EGFR-mutant advanced or metastatic non–small cell lung cancer displaying CNS metastases.

FDA Approves New Drug Labeling for Fludarabine Phosphate in CLL

November 20th 2024

Caroline Seymour

The FDA has approved revised drug labeling for fludarabine phosphate under Project Renewal.

Fox Chase Cancer Center Researcher Find New Treatment Targets in Microenvironment of Small Cell Lung Cancer

November 20th 2024

Fox Chase Cancer Center

Parth A. Desai, MBBS, MD, was first author on a study that detailed significant findings in small cell lung cancer.

Cancer Clinical Trials: A Relevant Need to Clearly Define the Value to Individual Patients

November 20th 2024

Maurie Markman, MD

Serious questions must be asked about the current state of interventional trials in the oncology sphere and how to improve their future value.

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